Laryngeal Xanthogranulomatosis: A Case Report

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Submitted: August 6, 2024
Published: Aug 23, 2024
DOI: 10.29328/journal.hor.1001028
Keywords:
Xanthogranuloma, Histiocytes, Larynx, Transoral epiglottectomy

Main Article Content

Micaela Redivo
Residents, ENT Department, Hospital Italiano de Buenos Aires, Argentina
María del Pilar Mingheira
Residents, ENT Department, Hospital Italiano de Buenos Aires, Argentina
Federica Fernandez Long
Residents, ENT Department, Hospital Italiano de Buenos Aires, Argentina
Carlos Santiago Ruggeri
Staff Physician, ENT Department, Hospital Italiano de Buenos Aires, Argentina

Abstract

Xanthogranulomatosis is an uncommon disease affecting non-Langerhans histiocytes.


Laryngeal involvement is very rare.


We describe the clinical case of an adult patient with disseminated xanthogranulomas affecting the supraglottic region of the larynx, leading to thickening and immobility of the epiglottis. The patient experienced inspiratory dyspnea on exertion. A transoral supraglottic epiglottectomy was performed, and a tracheostomy was subsequently required.

Article Details

Redivo, M., Mingheira, M. del P., Long, F. F., & Ruggeri, C. S. (2024). Laryngeal Xanthogranulomatosis: A Case Report. Heighpubs Otolaryngology and Rhinology, 8(1), 001–003. https://doi.org/10.29328/journal.hor.1001028
Case Reports

Copyright (c) 2024 Redivo M, et al.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Li S, Weidenbecher M. Adult onset xanthogranuloma presenting as laryngeal mass. Am J Otolaryngol Head Neck Med Surg. 2015;36(1):84-86. Available from: https://doi.org/10.1016/j.amjoto.2015.10.003

Weitzman S, Jaffe R. Uncommon histiocytic disorders: the non-Langerhans cell histiocytosis. Pediatr Blood Cancer. 2005;45(3):256-264. Available from: https://doi.org/10.1002/pbc.20246

Luder CM, Nordmann TM, Ramelyte E, Mühleisen B, Kerl K, Guenova E, et al. Histiocytosis – cutaneous manifestations of hematopoietic neoplasm and non-neoplastic histiocytic proliferations. J Eur Acad Dermatol Venereol. 2018;32(1):926-934. Available from: https://doi.org/10.1111/jdv.14794

Popa LL, Mihai MM, Orzan LO, Beiu C, Tebeica T, Giurcaneanu C. Adult onset xanthogranuloma – case report and review of literature. Rev Med Rom. 2019;66(4):22-30. Available from: https://rmj.com.ro/articles/2019.4/RMJ_2019_4_Art-22.pdf

Meyer SN, Vaughn A, Li Y, Studer AC, Rauen KA, Kiuru M. The association between juvenile xanthogranulomas in neurofibromatosis type 1 patient and the development of leukemia: A systematic review. J Eur Acad Dermatol Venereol. 2023;37(12). Available from: https://doi.org/10.1111/jdv.19321

Velletrani GL, Francavilla B, Rosati V, Padial B, Anemona L, Di Girolamo S. Adult onset xanthogranuloma presenting as a solitary laryngeal localization: case report and review of literature. Arch Clin Cases. 2022;9(4):145-149. Available from: https://doi.org/10.22551%2F2022.37.0904.10221