Research Article

Benign Paroxysmal Positional Vertigo (BPPV) and microvasculitis: A comparative study between nasal cytology and pathology

Armone Caruso Arturo*, Del Prete Salvatore, Marasco Daniela, Veronica Viola, Sabato Leo, Andrea Fulgione, Daniele Naviglio and Monica Gallo

Published: 24 February, 2020 | Volume 4 - Issue 1 | Pages: 001-005

Purpose: Benign paroxysmal positional vertigo (BPPV) is the most frequent peripheral vertigo syndrome in otoneurological clinical practice and is characterized by short and paroxysmal objective vertigo crises caused by changes in the position of the head on specific planes of space. Secondary microvasculitis is characterized by inflammatory destruction of the small vessels. Starting from this point, this work is based on the research of correlation between microvasculitis (especially secondary), recurrent BPPV and nasal cytology, an aspect, among other things, poorly documented.

Materials and methods: To evaluate the relationships between recurrent BPPV and secondary microvasculitis, nine patients with this disorder, 5 males and 4 females aged between 25 and 40 years were observed (average age 30.6). Non allergic pains in the small joints and in the anamnesis nothing relevant in the gentiles and collaterals: Evaluated with vestibular audiometric examination, nasal cytology and vascular examination with corneal HRT results. Nasal cytology, in all cases, has documented the presence of rare mast cells. The hemodynamics of the microcirculation with a confocal microscope has revealed blood flow alteration in all subjects.

Discussion: Analyzing the results, both the prevalence of the right side and a close relationship between vasculitis and BPPV could be seen.

Conclusion: The study of the nasal mucosa and the research of inflammatory cells could be fundamental for the study of BPPV in which as we have seen the important biochemical role for the onset of these diseases.

Read Full Article HTML DOI: 10.29328/journal.hor.1001017 Cite this Article Read Full Article PDF


Vasculitis: Mastocites; BPPV; Nasal cytology; Confocal microscope


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